There have been many hypotheses put out to explain the cause of autism spectrum disorder (ASD). Genetic predispositions, autoimmunity, viral infections and some medications have all been suggested causes. A latest theory connects ASD symptoms with disorders of the digestive system and the intestinal bacterial flora.
Autism in children has increased significantly over the last few years. Eating disorders and ailments of the gastrointestinal system are a common affliction among these children.
One of the theories discussed on the cause of autism spectrum disorder (ASD) is based on the gut-brain axis term, which describes the interaction between the gastrointestinal and nervous track. This axis is a two-way communication between central nervous system (CNS) and gut innervation. Mechanisms of this dependency include effects of neurological, immunological and hormonal mediators.
A study published in the journal Bio-Algorithms and Med-Systems demonstrates the differences in behavior habits, interest in nutrition, and frequency of consumption of food products between children suffering from ASD and healthy children.
Among patients with ASD, mucosal permeability is frequently diagnosed, which may be caused by chronic inflammation. Such inflammation can damage cells of intestinal membrane. Children with ASD also have a different composition of intestinal and gastric flora to non-sufferers.
Also, a greater permeability of the intestinal membrane may lead to penetration into the blood excessive exogenous peptides, which are not completely hydrolyzed due to impaired digestion of inter alia casein and glutamine in light of gut. They are transferred together to the brain, where they pass through the blood-brain barrier as neuro- and immuno-active substances, which interact with the CNS through disturbance of neurological mechanisms and brain development.
Healthy diet can help reduce digestive problems
Children with ASD have frequently problems with their digestive system, such as constipation, diarrhea, bloating, esophagitis or reflux. Due to the fact that any changes may affect their digestive system and as a result these may increase both incidence and severity of other disorders accompanying ASD, appropriate nutrition should play an important role, not only in order to minimize any digestive nuisances, but also to decrease any psychiatric symptoms. This could improve not only comfort of living but also overall health of people with ASD.
Read the original article here